AMDave
09-22-2020, 10:50 AM
Coronavirus update from David Baker. Thank you all for your contributions!
Here is a short video of David Baker describing some exciting results from de novo designs targeting SARS-Cov-2.
Thank you all for your contributions to this research! Although R@h was not directly used for the work described in the publication (link provided below), R@h was used for designing relevant scaffolds. Additionally, there are currently many similar designs that bind SARS-Cov-2 and related targets that were engineered using R@h.
https://www.youtube.com/embed/ODEIN5V3yLg
More information is available from the publication, De novo design of picomolar SARS-CoV-2 mini protein inhibitors (https://science.sciencemag.org/content/early/2020/09/08/science.abd9909).
More... (https://boinc.bakerlab.org/rosetta/forum_thread.php?id=14226)
Here is a short video of David Baker describing some exciting results from de novo designs targeting SARS-Cov-2.
Thank you all for your contributions to this research! Although R@h was not directly used for the work described in the publication (link provided below), R@h was used for designing relevant scaffolds. Additionally, there are currently many similar designs that bind SARS-Cov-2 and related targets that were engineered using R@h.
https://www.youtube.com/embed/ODEIN5V3yLg
More information is available from the publication, De novo design of picomolar SARS-CoV-2 mini protein inhibitors (https://science.sciencemag.org/content/early/2020/09/08/science.abd9909).
More... (https://boinc.bakerlab.org/rosetta/forum_thread.php?id=14226)